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[Modafinil Achat]

Le modafinil est un dГ©rivГ© mГ©thylГ© d'un amide et est gГ©nГ©ralement administrГ© par voie orale. Ces sels sont appelГ©s modafinil. La molГ©cule de modafinil est un composГ© hautement lipophile, qui a la capacitГ© de traverser la barriГЁre hГ©mato-encГ©phalique, contrairement Г  de nombreux mГ©dicaments de sa classer. ComparГ© Г  l'amphГ©tamine, le modafinil a une durГ©e d'action plus longue. Le 6-hydroxy-modafinil est ensuite conjuguГ© dans le foie en conjuguГ©s de glycine et de taurine qui sont excrГ©tГ©s par les reins. https://goodygirls.org/approvepost.asp? ... =guestbook http://wordpress.gena2018115rus.net/ear ... ent-536393 https://bordercollieconsigli.it/il-bord ... ent-581222 http://goodygirls.org/approvepost.asp?I ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://104.194.71.151/wordpress/?p=33&u ... ment-12200 https://goodygirls.org/approvepost.asp? ... =guestbook https://essayruler.com/blog/how-to-cite ... ent-236829 https://goodygirls.org/approvepost.asp? ... =guestbook http://jin-jay.nl/geboortekaartje/comme ... ent-314671 https://archiwum.pion.pl/web/node/450?p ... nt-6821566 http://netzwerkerei.de/2019/03/22/konta ... ent-292929 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://giravite.com/uncategorized/i-mig ... ent-420994 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://iedsanjosepuebloviejo.edu.co/202 ... omment-666 https://goodygirls.org/approvepost.asp? ... =guestbook http://pl-health.com/black-latte-polska ... ent-119833 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://atomikal.com/blog/llevando-calo ... mment-1768 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://corinaurbina.cl/?page_id=9&cpage ... ment-62553 https://rusportsblog.ru/boks/chisora-v- ... ment-19309 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://tanka99best.com/2022/08/20/%e3% ... ent-655065 http://effapp.com/development_skills/41 ... ment-87486 https://comfort-service-ufa.ru/otzyivyi ... ment-37991 https://3-5sfg.net/index.php?action=profile;u=1491502 https://goodygirls.org/approvepost.asp? ... =guestbook https://flamencochic.com/membeli-drone- ... omment-215 https://goodygirls.org/approvepost.asp? ... =guestbook https://shopaholicsecrets.com/paris-sou ... ment-30219 https://goodygirls.org/approvepost.asp? ... =guestbook https://lemurmuredesstatues.fr/elsa-aub ... ent-267050 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook Il est important que les patients soient surveillГ©s et qu'ils obtiennent un test sanguin pour s'assurer qu'ils n'ont pas de trouble sanguin grave ou d'autres problГЁmes de santГ© graves. Le modafinil ne doit pas ГЄtre administrГ© Г  une personne souffrant de problГЁmes rГ©naux ou hГ©patiques. Normalement, moins de 25 % de la population souffre de ce trouble et pour qu'il soit diagnostiquГ©, la personne doit avoir une somnolence excessive avec ou sans diminution du besoin de sommeil. Il est disponible en tant que mГ©dicament gГ©nГ©rique.

[DavidVab]

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[Modafinil Achat]

Bien qu'il ait Г©tГ© utilisГ© hors AMM comme prГ©tendu activateur cognitif pour amГ©liorer l'Г©veil dans des Г©tudes animales et humaines, la recherche sur son efficacitГ© pour cette utilisation n'est pas concluante. Le modafinil est quelque peu controversГ© en raison de son utilisation dans le traitement des personnes souffrant d'un manque de sommeil, car son efficacitГ© en tant qu'amplificateur de la cognition reste Г  prouver. Le modafinil doit ГЄtre utilisГ© avec prudence par les personnes atteintes d'une maladie du foie ou qui prennent des mГ©dicaments susceptibles d'interagir avec lui. Le mГ©canisme exact n'est pas clair, mais il peut augmenter l'Г©veil en modulant les neurotransmetteurs dans le cerveau. Il a une exigence facultative pour l'achat d'une ordonnance, car il est classГ© comme substance contrГґlГ©e de l'annexe IV. Ceci est rГ©alisГ© par une action spГ©cifique sur les rГ©cepteurs de la dopamine D2 dans l'hypothalamus et d'autres parties du cerveau. Il a Г©tГ© approuvГ© pour une utilisation hors indication pour le traitement de la somnolence associГ©e au trouble du sommeil liГ© au travail postГ© (SWED) aux Г‰tats-Unis en 2004. https://goodygirls.org/approvepost.asp? ... =guestbook https://blog.ynotfly.com/traveler-tips/ ... ment-59454 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://inchatham.com/secu-9-12-2019/?un ... nt-1560555 https://goodygirls.org/approvepost.asp? ... =guestbook https://myflirtstore.com/sex-in-a-car/? ... ent-216169 https://goodygirls.org/approvepost.asp? ... =guestbook http://kdjapan.net/hyogo/album/album.cg ... ail&no=221 https://goodygirls.org/approvepost.asp? ... =guestbook https://galleryjeans.ch/blog/?attachmen ... ent-152316 https://deco-hogar.net/muebles-para-cas ... ent-372458 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://changingthescript.com/getting-a- ... ent-180353 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://pos.net.pk/6/?unapproved=24832&m ... ment-24832 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://alwaysgotogether.com/sheraton-hu ... nt-5191017 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://dreaming.co.il/%d7%97%d7%9c%d7% ... ment-46874 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://goodygirls.org/approvepost.asp?I ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://elizabethymike.sweeteventscr.com ... ent-399420 https://arya-tv.com/shraddha-kapoor-bro ... ment-17299 http://redisfans.com/?page_id=4&unappro ... ent-376826 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://archiwum.pion.pl/web/node/217?p ... nt-6830354 https://goodygirls.org/approvepost.asp? ... =guestbook https://ausamachar.com/noise-launches-n ... ment-23193 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://americas-table.com/blog/thank-y ... ent-520769 https://cracked.sx/member.php?action=profile&uid=60475 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://battleroyaleforums.com/ring-of- ... nt-2579392 https://xn--90abkoecs5aode7g.xn--p1ai/8 ... ment-29730 https://goodygirls.org/approvepost.asp? ... =guestbook http://archiwum.pion.pl/web/node/599?pa ... nt-6821737 http://bpfasteners.com/bp-303-manual_th ... ent-313040 https://thetrip.guide/%e3%80%90%e6%8e%a ... omment-274 https://asteringenieria.com/portfolio/b ... ment-52658 https://luxcloudhost.com/2013/09/post-w ... ment-10127 Le modafinil est un stimulant du SNC qui se lie spГ©cifiquement aux transporteurs de la dopamine dans le cerveau, ainsi qu'aux transporteurs du glutamate. Les symptГґmes de surdosage peuvent inclure une agitation, une augmentation de la tempГ©rature corporelle, une augmentation de la pression artГ©rielle, une accГ©lГ©ration du rythme cardiaque, une transpiration excessive, des nausГ©es, des vomissements et des hallucinations visuelles ou mentales. MГ©dicalement appelГ© modafinil ou chlorhydrate de 2-benzyl-1,5-dimГ©thyl-hexahydro-1,5-diazocinoheptadiГЁne-4-one, le modafinil est un mГ©dicament dГ©livrГ© sur ordonnance. Une Г©tude de 2005 utilisant le modafinil ou d'autres mГ©dicaments a rГ©vГ©lГ© qu'il aidait Г  amГ©liorer la cognition chez les personnes atteintes de schizophrГ©nie, probablement en raison de changements dans les niveaux d'adГ©nosine dans le cerveau. S'il n'est pas pris le matin, il a tendance Г  perdre de son efficacitГ©.

[Modafinil Achat]

Les comprimés sont solubles dans l'eau et facilement écrasés. Il existe certaines preuves que le modafinil peut être un substitut du médicament Adderall chez les personnes qui souffrent d'un manque d'attention. Votre médecin peut vous demander d'utiliser le modafinil par intermittence ou d'éviter de le prendre. La plupart du modafinil vendu en ligne est de 100 mg, et il est généralement vendu à des prix d'environ 120 $ pour 100 gélules. La consommation de caféine n'est souvent pas réduite. https://goodygirls.org/approvepost.asp? ... =guestbook http://socialimpactready.com/forums/use ... finil-2022 https://sawsanzakaria.com/accomodation- ... ment-12117 http://vibestash.com/product/skull-head ... ment-63089 http://ddk-fotografie.nl/?unapproved=11 ... ent-110359 https://goodygirls.org/approvepost.asp? ... =guestbook https://thedesignbridge.in/blog/everyth ... nt-1203282 https://goodygirls.org/approvepost.asp? ... =guestbook https://littlechampsedu.com/hello-world ... ent-147888 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://blog.robustastudio.com/e-commer ... ent-390830 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://kmkl.ocean.itb.ac.id/terbitnya- ... ent-207732 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://susannaloves.com/2013/01/30/hell ... ent-196684 http://bringithomeagain.com/items-for-s ... ent-586690 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://tireseinen.com/avoideigodenwa/?u ... omment-450 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://hodgeon7th.com/blog/featured/ho ... ent-206345 https://goodygirls.org/approvepost.asp? ... =guestbook http://blog.tzyyng.com/archives/1612/co ... nt-5035427 https://goodygirls.org/approvepost.asp? ... =guestbook https://ninjabeef.com/uvey-babasini-ann ... ent-247310 https://klimatekspert.uz/plyusy-i-minus ... ent-151983 https://expedicia.org/ukrainski-slidi-u ... ment-73069 https://goodygirls.org/approvepost.asp? ... =guestbook http://kbcd.nodong.org/wordpress/?p=870 ... mment-2432 https://goodygirls.org/approvepost.asp? ... =guestbook http://goodygirls.org/approvepost.asp?I ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://jonakyblog.com/japanese-garden- ... ment-27492 Il est actif lorsqu'il est consommé et s'est avéré influencer plusieurs récepteurs dans le cerveau, y compris la dopamine, la sérotonine et l'adénosine, avec des effets variables. Le modafinil affecte la libération des neurotransmetteurs en modulant les canaux calciques sensibles au voltage au niveau du terminal présynaptique. La cocaïne et les amphétamines sont utilisées depuis longtemps comme drogues de fête populaires et sont connues pour améliorer l'éveil. Il est conçu pour augmenter l'éveil et soulager la somnolence. Le résultat de ce métabolisme est une augmentation du normodafinil, qui est le métabolite pharmacologiquement actif.

[Modafinil Achat]

Bien que la libГ©ration de dopamine soit l'objectif habituel du modafinil, il agit comme un agoniste faible des rГ©cepteurs de dopamine 1, 2 et 5. Il est Г©galement conseillГ© aux personnes souffrant de dГ©pression et d'autres problГЁmes de santГ© mentale et aux adolescents prenant des mГ©dicaments pour le TDAH d'utiliser le modafinil avec prudence en raison de son potentiel d'augmentation ou de diminution de ces conditions. Il est Г©galement recommandГ© pour le traitement Г  court terme des personnes souffrant de somnolence diurne excessive. La dose initiale est de 200 mg et la dose peut ГЄtre augmentГ©e Г  des intervalles de 200 mg jusqu'Г  une dose quotidienne maximale de 400 mg selon les individus. cafГ©ine. 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Pour cette raison, la prise de modafinil au moins 4 heures avant le coucher peut ГЄtre nГ©cessaire pour un effet maximal. Pour la narcolepsie, il peut Г©galement rГ©duire la somnolence diurne due aux hallucinations hypnagogiques, qui sont des sensations anormales, comme entendre des voix ou voir des lumiГЁres, gГ©nГ©ralement peu de temps avant de s'endormir. Les principales propriГ©tГ©s pharmacologiques du modafinil sont sa capacitГ© Г  ГЄtre un antagoniste doux et sГ©lectif des rГ©cepteurs alpha-1 adrГ©nergiques.

[DavidVab]

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[Modafinil Achat]

Il est Г©galement disponible sur ordonnance dans d'autres pays via des pharmacies en ligne. Le modafinil a Г©tГ© utilisГ© hors indication pour d'autres troubles du sommeil et de l'Г©veil diurne, tels que le somnambulisme et les troubles du rythme circadien. Ses effets sur le cerveau ressemblent beaucoup Г  l'Г©tat de veille, mais ses effets sur le corps sont assez diffГ©rents. Il existe Г©galement une version gГ©nГ©rique vendue sous la marque Modalert. Le modafinil est utilisГ© hors AMM pour amГ©liorer l'attention, la concentration, la motivation et l'Г©veil. https://goodygirls.org/approvepost.asp? ... =guestbook https://frokeninvestera.se/kryptovaluto ... ment-70066 https://m0nksy.com/2020/03/14/st-exampl ... omment-252 https://cungbatchu.com/index.php/2019/1 ... ment-47529 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://brookersofbluntys.co.uk/buffalo- ... ent-521328 https://goodygirls.org/approvepost.asp? ... =guestbook https://morijstyle.com/hello-world/?una ... mment-2785 https://goodygirls.org/approvepost.asp? ... =guestbook http://cheneywa.us/MyBB/member.php?acti ... &uid=28804 https://thisismotherhoodblog.com/djjohn ... mment-1338 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://holystory-blog.com/hello-world/ ... mment-2575 https://berlin-eurologistik.de/forum/me ... &uid=21582 http://socialimpactready.com/forums/use ... finil-2022 http://xn----ytbba6as.xn--p1ai/2021/01/ ... nt-4313435 https://duos.sk/blog/sialeny-april-je-t ... ent-186289 https://archiwum.pion.pl/web/node/447?p ... nt-6821662 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://look5.com.tw/news/employer-news ... ment-27092 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://gokulcruise.com/best-time-to-vi ... mment-3402 https://findbestfirms.com/how-to-begin- ... omment-245 http://blog.tzyyng.com/archives/1612/co ... nt-5035427 https://immuneliving.com/hello-world/?u ... mment-7498 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://lesnay-sloboda.ru/component/kune ... finil-2022 https://usdnaira.com/blog/domiciliary-a ... ia?page=79 http://lindybop.se/?unapproved=376377&m ... ent-376377 https://goodygirls.org/approvepost.asp? ... =guestbook https://situazion.info/2019/10/17/25-%d ... ment-31573 https://goodygirls.org/approvepost.asp? ... =guestbook http://slimolifilho.com/index.php/jeux- ... ent-807139 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://jamonibericoonline.com/rollitos ... ent-160688 https://goodygirls.org/approvepost.asp? ... =guestbook https://staffoflifefarms.com/product/po ... ent-174555 https://goodygirls.org/approvepost.asp? ... =guestbook https://scoliosiscorrectioncenter.com/r ... ent-153213 https://ceramahmotivasi.com/2016/12/tak ... t-10994676 https://homemoneycy.com/diy/%ce%b3%cf%8 ... ent-363470 https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook https://goodygirls.org/approvepost.asp? ... =guestbook http://dahliacanny.com/uncategorized/pr ... mment-1997 http://carbondetonation.com/2018/10/07/ ... ent-250683 Le modafinil n'est pas un sГ©datif et les personnes qui en prennent ne semblent pas avoir de difficultГ© Г  conduire. Le modafinil est utilisГ© pour traiter la somnolence (hypersomnie) rГ©sultant d'une insuffisance de sommeil naturel et est indiquГ© dans le traitement de la narcolepsie et des troubles du sommeil liГ©s au travail postГ©, pour amГ©liorer l'Г©tat d'Г©veil et la vigilance diurne lors de voyages Г  travers diffГ©rents fuseaux horaires, pour amГ©liorer l'Г©tat de veille chez les personnes souffrant de l'apnГ©e obstructive du sommeil et pour traiter les patients souffrant d'un trouble dГ©ficitaire de l'attention avec hyperactivitГ© (TDAH). Au niveau cellulaire, il a Г©tГ© dГ©montrГ© que le modafinil active les rГ©cepteurs D-1, la stimulation des rГ©cepteurs D-1 entraГ®nant une augmentation de la libГ©ration de glutamate dans la rГ©gion tegmentale ventrale et une diminution de la libГ©ration dans l'hypothalamus. La FDA approuve le modafinil pour son utilisation dans le traitement de la somnolence due Г  la narcolepsie et aux troubles du sommeil liГ©s au travail postГ©. Le modafinil ne semble pas ГЄtre utilisГ© lorsque la personne n'a pas sommeil.

[DavidVab]

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[Modafinil Achat]

Le médicament a été inventé dans les années 1970 par le neuroscientifique français Michel Jouvet du Centre de recherche de La Rochelle et la société pharmaceutique française Laboratoires Lafon, et lancé en 1987. Le modafinil a été prescrit à des doses de 100 à 300 mg, bien que des doses plus élevées allant jusqu'à 400 mg ne soient pas rares. Il ne semble pas altérer la sensibilité des récepteurs ou provoquer une désensibilisation des récepteurs. Le modafinil inhibe le transporteur de la dopamine avec une IC50 de 57 nM et une valeur Ki de 200 nM. Dans une revue médicale, les États-UnisLa Food and Drug Administration (FDA) note que le modafinil est "bien toléré" et "peut avoir moins, voire aucun, des effets indésirables observés avec les stimulants commercialisés pour le traitement du trouble d'hyperactivité avec déficit de l'attention (TDAH)", y compris "mauvais rêves, bouche sèche, somnolence, maux de tête, cauchemars, agitation, hypertension artérielle, convulsions et insomnie. 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Le modafinil est également disponible sous forme de gélule à libération immédiate (IR) en deux dosages de 100 mg et 200 mg. En décembre 2014, l'Agence mondiale antidopage a publié un rapport, Modafinil : un stimulant cérébral aux propriétés d'amélioration cognitive, qui comprenait de nouvelles preuves scientifiques montrant que le modafinil n'est pas un médicament destiné à améliorer les performances sur ordonnance et qu'il n'existe aucune donnée suggérant qu'il s'agit d'un agent dopant. Il est également utilisé comme stimulant cognitif pour augmenter l'éveil et par les personnes atteintes de TDAH. L'autre nom de marque du modafinil est Aptensio XR, vendu sous le nom générique Alertec.

[DavidVab]

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