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Le modafinil est commercialisé comme nootropique pour l'amélioration de l'éveil depuis plus d'une décennie. Les stimulants du SNC augmentent l'éveil, l'attention et/ou l'irritabilité et sont utilisés pour traiter la somnolence due à la narcolepsie, les troubles du sommeil liés au travail posté et l'apnée obstructive du sommeil. Un certain nombre d'essais cliniques ont démontré que le modafinil peut être un traitement efficace pour les personnes atteintes de TDAH. Les effets les plus constants du modafinil sont légers et comprennent une activité et un éveil accrus, ainsi qu'un éveil pendant la journée. Il a été démontré que le modafinil améliore les performances de certains tests conçus pour mesurer l'attention et la concentration. 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Si vous ressentez peu ou pas de somnolence une fois la période écoulée, la posologie peut être réduite ou supprimée complètement. Alors que la FDA a approuvé le médicament pour l'insomnie, les informations de prescription officielles du médicament ont appelé à une évaluation simultanée du temps de sommeil total pour garantir le respect du temps de sommeil prescrit. La CDC recommande également que les personnes qui demandent une ordonnance pour le modafinil appellent leur fournisseur de soins médicaux pour vérifier la prescription et avertir le fournisseur des symptômes. Utilisé pour le traitement de la narcolepsie, un trouble du sommeil qui présente certains des mêmes symptômes que le TDAH, le modafinil est efficace pour augmenter l'éveil.
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